李万方

发布时间:2021-09-13 浏览次数:10

 

李万方

职称

副教授

任职

 

导师类型

硕士生导师

所属学科专业

有机化学

电话

13818602564

邮箱

lwf@usst.edu.cn

一、学习工作经历

2018.12–至今

上海理工大学化学系

副教授

2018.05–2018.11

上海交通大学化学化工学院

研究助理

2015.10–2018.04

新加坡国立大学化学系

有机化学、博士后

2013.10–2015.09

德国莱布尼兹催化研究所 

均相催化、博士后

2007.09–2013.06

上海交通大学化学化工学院

应用化学、博士

2003.09–2007.06

南京工业大学理学院

轻化工程、本科

二、研究方向

(1) 过渡金属(特别是廉价金属)催化的有机合成方法学研究;

(2) 绿色、经济的新型有机合成反应与合成试剂的开发与应用;

(3) 面向医药分子、有机光电、能源材料的合成路线设计和中间体研究。

三、科研成果

本人主要关注过渡金属催化的有机合成方法学及其在医药中间体、功能材料等合成中的应用。博士期间从事了Ru催化的羰基不对称氢化研究;博士后工作期间又继续从事了 PdNi等过渡金属催化的羰基化、氢甲酰化、偶联反应等方面的研究。2011年至今,在本专业领域国际知名期刊《Angew. Chem. Int. Ed.》,《Chem. Sci》,《Org. Lett.》,Chem. Commun.》等发表研究论文30余篇,他引次数累计500余次,入选2019年度ESI高被引论文1篇。目前主持国家自然科学青年基金1(21901163)、曾参与国家自然科学科学基金面上项目、重点项目3项。

代表性项目:

(1) 国家自然科学青年基金 (21901163, 2020–2022) 25万元,主持,《镍催化炔烃三组分偶联反应构建官能化四碳取代烯烃的研究》;

(2) 上海市高校青年东方学者岗位计划支持项目(QD2019024,   2020–2022)30万元,主持。

代表性科研论文:

(1) Xiaoqiang Wu;   Purui Zheng; Wanfang Li*;   Tao Xu*, Reductive Cross-Coupling to Access C–N Bonds from Aryl   Halides and Diazoesters under Dual Nickel/Photoredox-Catalyzed Conditions, Org. Chem. Front.2021, 8, 4118–4123.

(2) Wanfang Li*; Shun   Yu; Jincan Li; Yu Zhao*, Nickel-Catalyzed Allylmethylation of Alkynes   Using Allylic Alcohols and AlMe3: A Facile Access to Skipped   Dienes and Trienes, Angew. Chem. Int.   Ed.2020, 59, 14404–14408.

(3) Jincan Li; Yan   Zheng; Mingxian Huang; Wanfang Li*,   Ni-Catalyzed Denitrogenative Cross-Coupling of Benzotriazinones and Cyclopropanols:   An Easy Access to Functionalized β-Aryl   Ketones, Org. Lett.2020, 22, 5020–5024.

(4) Wanfang Li; Bin Lu; Xiaomin   Xie; Zhaoguo Zhang*, Ru-Catalyzed Chemo- and Enantioselective   Hydrogenation of β-Diketones   Assisted by the Neighboring Heteroatoms, Org.   Lett.2019, 21, 5509–5513.

(5) Wanfang Li; Jie Kang Boon; Yu   Zhao*, Nickel-Catalyzed Difunctionalization of Allyl Moieties   Using Organoboronic Acids and Halides with Divergent Regioselectivities, Chem. Sci.2018, 9, 600–607.

(6) Wanfang Li; Xiao-Feng Wu*   In Transition Metal Catalyzed   Carbonylative Synthesis of Heterocycles; Wu, X.-F., Beller, M., Eds.;   Springer International Publishing: 2016;   Vol. 42, pp 55–87.

(7) Wanfang Li; Bin Lu; Zhaoguo   Zhang*, A Decennary Journey towards the Efficient Asymmetric   Hydrogenation of Highly Functionalized Ketones, Chem. Rec.2016, 16, 2506–2520.

(8) Wanfang Li; Xiao-Feng Wu*,   Ruthenium-Catalyzed Conjugate Hydrogenation of α,β-Enones by in situ   Generated Dihydrogen from Paraformaldehyde and Water, Eur. J. Org. Chem.2015,   2015, 331–335.

(9) Wanfang Li; Xiao-Feng Wu*,   Palladium-Catalyzed Carbonylative Sonogashira Coupling between Aryl Triazenes   and Alkynes, Org. Biomol. Chem.2015, 13, 5090–5093.

(10) Wanfang Li; Xiao-Feng Wu*,   Palladium-Catalyzed Aminocarbonylation of N-Chloroamines   with Boronic Acids, Chem. Eur. J.2015, 21, 7374–7378.

(11) Wanfang Li; Xiao-Feng Wu*,   N2 Extrusion and CO Insertion: A Novel Palladium-Catalyzed   Carbonylative Transformation of Aryltriazenes, Org. Lett.2015, 17, 1910–1913.

(12) Wanfang Li; Xiao-Feng Wu*,   A Practical and General Base-Catalyzed Carbonylation of Amines for the   Synthesis of N-Formamides, Chem. Eur. J.2015, 21, 14943–14948.

(13) Wanfang Li; Xiao-Feng Wu*,   The Applications of (Para)formaldehyde in Metal-Catalyzed Organic Synthesis, Adv. Synth. Catal.2015, 357, 3393–3418.

(14) Wanfang Li; Xiao-Feng Wu*,   Palladium-Catalyzed Carbonylative Synthesis of Benzoxazinones from N-(o-Bromoaryl)amides   Using Paraformaldehyde as the Carbonyl Source, J. Org. Chem.2014, 79, 10410–10416.

(15) Wanfang Li; Haoquan Li; Peter   Langer; Matthias Beller; Xiao-Feng Wu*, Palladium-Catalyzed   Aminosulfonylation of Aryl Iodides by Using Na2SO3 as   the SO2 Source, Eur. J. Org.   Chem.2014, 2014, 3101–3103.

(16) Wanfang Li; Matthias Beller;   Xiao-Feng Wu*, Catalytic Conversion of Aryl Triazenes into Aryl   Sulfonamides Using Sulfur Dioxide as the Sulfonyl Source, Chem. Commun.2014, 50, 9513–9516.

(17) Wanfang Li; Xiaomin Xie;   Xiaoming Tao; Xin Ma; Weizheng Fan; Xiaoming Li; Zhaoguo Zhang*,   RuCl2(PPh3)3-Catalyzed Chemoselective   Hydrogenation of β,δ-Diketo Acid   Derivatives at the β-Carbonyls, RSC Adv.2012, 2, 3214–3216.

(18) Wanfang Li; Xiaoming Tao; Xin   Ma; Weizheng Fan; Xiaoming Li; Mengmeng Zhao; Xiaomin Xie; Zhaoguo Zhang*,   Ruthenium-Catalyzed Asymmetric Hydrogenation of 3-Oxoglutaric Acid   Derivatives: A Study of Unconventional Solvent and Substituent Effects, Chem. Eur. J.2012, 18, 16531–16539.

(19) Wanfang Li; Weizheng Fan; Xin   Ma; Xiaoming Tao; Xiaoming Li; Xiaomin Xie; Zhaoguo Zhang*,   Ru-Catalyzed Hydrogenation of 3,5-Diketo Amides: Simultaneous Control of   Chemo- and Enantioselectivity, Chem.   Commun.2012, 48, 8976–8978.

(20) Wanfang Li; Xin Ma; Weizheng   Fan; Xiaoming Tao; Xiaoming Li; Xiaomin Xie; Zhaoguo Zhang*,   Ru-Catalyzed Asymmetric Hydrogenation of 3-Oxoglutaric Acid Derivatives via   Solvent-assisted Pinpoint Recognition of Carbonyls in Close Chemical   Propinquity, Org. Lett.2011, 13, 3876–3879.

 

代表性专利:

 

四、学术任职

中国化学会会员

 

五、授课情况

(1) 本科生:《有机化学》、《金属有机化学》、《有机化学实验》等

(2) 研究生:《现代有机合成化学》

六、获奖情况

(1) 2019年:上海市高校青年东方学者;

(2) 2019年:上海理工大学青年教师教学竞赛二等奖;

(2) 2016年:14届华人有机化学会议(ISCOC–14)优秀墙报奖;

(3) 2014年:德国莱布尼兹学会博士后奖学金;

(4) 2013年:入选中国优秀博士生代表团,赴德国参加63届林岛诺贝尔奖得主大会(国家自然科学基金委中德科学中心选拔与资助,全国共25)